The Mediterranean diet is the healthiest diet for everyone.

The PREDIMED trial (Spain, 2013, retracted-and-republished 2018) is the largest randomised trial of a Mediterranean diet and showed a meaningful reduction in major cardiovascular events versus a low-fat comparator.

Subsequent meta-analyses confirm reduced cardiovascular risk and modest benefits in type 2 diabetes management. The pattern also has unusually good adherence in long-term studies — people stick with it.

Generalisation limits: trial cohorts skew European and middle-aged-or-older. Effects in other populations, in children, and against comparators other than 'low-fat Western diet' are less well-characterised. 'Healthiest for everyone' is therefore stronger than the evidence base.

The engine returns Mixed: the diet is robustly Supported as cardioprotective, while the universal-superiority framing is unsupported.

• NEJM, Estruch et al. (PREDIMED, 2018 republication)
  Large randomised trial
  Primary cardiovascular endpoint reduction.
• Cochrane Review, Rees et al. (2019)
  Systematic review
  Confirmed cardiovascular benefit; noted population narrowness.
• Advances in Nutrition, Dinu et al. (2018)
  Umbrella meta-analysis
  Compared dietary patterns; Mediterranean ranked highest for cardiovascular outcomes.